Warmi Clinical trials

Warmi® is comprised of vegetable (Lepidium Meyenii) and fruit extracts (Citrus Bioflavonoids). The efficacy and safety of its ingredient have been studied and published in respective scientific journal and symposium. However, the combination of extracts in Warmi® have been used in five preliminary, clinical trials, involving 229 women. The data from these studies have been presented in several menopause congresses.

Activity: A study of 122 women experiencing moderate to intense menopausal symptoms found that Warmi® significantly improved in changing mood (2 different measures), vasomotor (hot flashes/night sweats) symptoms and sexuality compared to baseline values. Sexual improvement included sexual fantasy, arousal, satisfaction, intercourse discomfort, orgasm frequency and vaginal dryness. Compared to baseline, Warmi® also improved somatic (sleep) measures at months 1 and 3 and quality of life measures (physical health, psychological, social relationships, general) at 6 months study period. Finally, cardiovascular, bone resorption and other hormonal balance markers statistically significant improvement was also observed, over baseline at 6 months in that study.

6 months treatment. Placebo n=39, Other n=40, Other n= 43. p ≤ 0.05

A study with 54 women experiencing severe menopausal symptoms found that the vegetable extract in Warmi® significantly improved the menopausal symptoms: overall, vasomotor, physical, psychosocial and sexual. Cardiovascular and hormonal balance markers also improved statistically, at 3 months.

6 months treatment. Placebo n=39, Other n=40, Other n= 43. p ≤ 0.05

More Effective than placebo? Yes (based on 1 study) statistically significant improvement versus placebo was seen starting at 3 months. Improved menopausal symptoms included mood, vasomotor (hot flashes/night sweats) and sexual (based on the Greene Climacteric Scale).1

Safety: Two studies involving 53 women 18 to 40 years old and 54 post menopausal women found Warmi® to be safe, even at double the recommended intake for 3 months. 

Response Time: Significant improvement baseline for several symptoms was noted at the first measurement period (1 month) and generally improved thereafter. Improvement to placebo was noted at 3 months and generally improved thereafter.

References

https://www.maturitas.org/article/S0378-5122(17)30657-6/fulltext

E. Malaga Correa, J. Osorio, A. Osorio, J. Fernandez, W. Cruz, E. Moya, P. A. Rojas, J. A. Brinckmann, M. Villar. 2017 The effect of natural supplement containing glucosinolates, β-sitosterol and citrus flavonoids over menopausal symptoms in postmenopausal women. Abstract/MATURITAS 103 (9017), 89-94.

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